What Does a Low Neutrophil count mean

By Max. D Gray. Updated: January 16, 2017
What Does a Low Neutrophil count mean

Neutrophils are the most common type of white blood cells in our blood, responsible for eliminating bacteria and other organisms that invade the body, preventing them from affecting our health. So, if after doing a blood test, it shows that neutrophil levels are low, it's important to determine the cause of this decline, in order to ensure the effectiveness of immune system function. At we'll explain some common reasons that explain why neutrophils are low.

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It's important to know what are considered normal neutrophil levels, to identify whether they are in fact low. Although blood tests can show these levels, they may vary slightly from one laboratory to another. Normal levels of neutrophils should be between 2000 and 7500 /ml, though a count of 1500 to 8000/ml is also acceptable. If the count is less than 2000 / ml, the white blood cell count is considered to be low.

The name given to low levels of neutrophils is Neutropenia, which can have several causes. This condition can cause bacteria that are normally in your body to become a risk of infection.


There are several reasons that may cause a decline in neutrophils or neutropenia, and the most common are the following:

  • The flu, especially with severe and persistent symptoms.
  • Vitamin deficiency.
  • A viral infection
  • Malaria.
  • Lyme disease
  • A moderate to severe bacterial infection or one that's widespread. This can include Salmonella.
  • Aplastic anemia, due to this condition affecting the bone marrow.
  • People suffering from rheumatoid arthritis may also experience a low neutrophil count.

We should note that a low neutrophil blood count may also be congenital. Kostman's syndrome is a condition where the body produces less neutrophils and Myelokathexis, a condition in which not enough neutrophils can enter the bloodstream.


Other more serious conditions that can lead to decreased levels of neutrophils in the blood include:

  • Leukaemia.
  • Damage to the bone marrow.
  • AIDS
  • Hepatitis A, B and C.
  • Hyperspleninsm.
  • Patients undergoing treatment for cancer, such as chemotherapy and radiotherapy.

Neutrophils are created in the bone marrow, which is why many diseases that affect the bone marrow involve a decrease in Neutrophil levels, as the production is disrupted in such case.


Since it's clear that there are various causes of low neutrophil levels, it's important that, if a blood test indicates a low white blood cell count, you consult a hematologist who will perform an exam to determine the reason for this decline.

You can also check our article on how to interpret a blood test or the normal range of eosinophils.

This article is merely informative, oneHOWTO does not have the authority to prescribe any medical treatments or create a diagnosis. We invite you to visit your doctor if you have any type of condition or pain.

If you want to read similar articles to What Does a Low Neutrophil count mean, we recommend you visit our Diseases & secondary effects category.

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Lisa Hendy
My daughter suffers from cold urticaria, and also gets blood rashes that don't disappear when pressure is applied. The latest rash of this kind appeared on both her shoulders and the only reason she could give was that a much smaller girl in her school had put her hands on my daughters shoulders and jumped up that same day. My daughter had blood tests at the end of 2017 and her WBC count had dropped from 8.4 to 4.7 in just over a year and her Neutrophils count had dropped from 3.5 to 1.9 and from what I understand from the normal ranges stated it should be 2.5-7.4 is this correct and should we be concerned in the drop especially considering her CU and the non blanching rashes?
OneHowTo Editor
Hi Lisa,

The normal neutrophil count is above 1,500/ml (1.5), so your daughter's level appears to be in a healthy range. However, the information we provide here is merely informative and should not be used in replacement of a qualified physician's advice. There are many other symptoms which need to be monitored and checked, they are the only ones who can do this. If your doctor did not explain or give any sort of evaluation when the readings were taken, you should go back to get it from them.

What Does a Low Neutrophil count mean
What Does a Low Neutrophil count mean

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